The urine/plasma electrolyte ratio: A predictive guide to water restriction

Howard Furst, Kenneth R. Hallows, Jarrod Post, Sheldon Chen, Wayne Kotzker, Stanley Goldfarb, Fuad N. Ziyadeh, Eric G. Neilson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

93 Scopus citations


Patients with hypotonic hyponatremia are encountered commonly in the general practice of medicine. Nearly all strategies for the management of subacute or chronic hyponatremia call for some amount of water restriction. The considerations for such a prescription have not been addressed in the literature. We describe therefore a simple approach grounded in the physiology of electrolyte-free water clearance that can be used at the bedside.

Original languageEnglish (US)
Pages (from-to)240-244
Number of pages5
JournalAmerican Journal of the Medical Sciences
Issue number4
StatePublished - Apr 2000


  • Electrolyte-free water clearance
  • Hyponatremia
  • Hypotonicity
  • Water intoxication

ASJC Scopus subject areas

  • Medicine(all)

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