The use of a durable right ventricular assist device for isolated right ventricular failure due to combined pre- and postcapillary pulmonary hypertension

Sirish Vullaganti, Anjan Tibrewala, Jonathan D Rich, Duc Thinh Pham, Stuart Rich*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Patients with isolated right ventricular (RV) failure have poor outcomes and minimal treatment options. We report a case where a durable RV assist device (RVAD) was implanted for end-stage RV failure from combined pre- and postcapillary pulmonary hypertension (PH) due in part to chronic thromboembolic PH using a temporary percutaneous RVAD as a bridging strategy. While the patient ultimately died from non-cardiovascular causes, there was significant improvement in markers of cardiogenic shock and hemodynamic RV function parameters without adverse effects from increased pulmonary artery pressures. More research is needed to identify an appropriate long-term mechanical support strategy for this patient population.

Original languageEnglish (US)
JournalPulmonary Circulation
Volume9
Issue number2
DOIs
StatePublished - Apr 1 2019

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Heart-Assist Devices
Pulmonary Hypertension
Right Ventricular Function
Cardiogenic Shock
Pulmonary Artery
Hemodynamics
Pressure
Equipment and Supplies
Research
Population

Keywords

  • CTEPH
  • PH
  • Protek Duo
  • RV failure
  • RVAD
  • mechanical circulatory support

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

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abstract = "Patients with isolated right ventricular (RV) failure have poor outcomes and minimal treatment options. We report a case where a durable RV assist device (RVAD) was implanted for end-stage RV failure from combined pre- and postcapillary pulmonary hypertension (PH) due in part to chronic thromboembolic PH using a temporary percutaneous RVAD as a bridging strategy. While the patient ultimately died from non-cardiovascular causes, there was significant improvement in markers of cardiogenic shock and hemodynamic RV function parameters without adverse effects from increased pulmonary artery pressures. More research is needed to identify an appropriate long-term mechanical support strategy for this patient population.",
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AB - Patients with isolated right ventricular (RV) failure have poor outcomes and minimal treatment options. We report a case where a durable RV assist device (RVAD) was implanted for end-stage RV failure from combined pre- and postcapillary pulmonary hypertension (PH) due in part to chronic thromboembolic PH using a temporary percutaneous RVAD as a bridging strategy. While the patient ultimately died from non-cardiovascular causes, there was significant improvement in markers of cardiogenic shock and hemodynamic RV function parameters without adverse effects from increased pulmonary artery pressures. More research is needed to identify an appropriate long-term mechanical support strategy for this patient population.

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