The use of epinephrine in the treatment of older adult asthmatics

Rita Cydulka*, Richard Davison, Leslie Grammer, Michele Parker, James Mathews IV

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


Three subcutaneous doses of 0.3 mL 1:1,000 epinephrine were given 20 minules apart to 95 adult asthmatics 15 to 96 years old during 108 asthma excerbations. Patients with a history of recent myocardial infarction or of angina were excluded from our study. Heart rhythm and rate, blood pressure, respiratory rate, and clinical response were prospectively evaluated before, during, and after the administration of epinephrine. Three was no significant difference in the occurrence of ventricular arrthymias between patients less than 40 and more than 40 years old. The mean systolic and diastolic blood pressures, mean heart rate, and mean respiratory rate decreased with treatment in the older population. Our results suggest that epinephrine in safe to use in acute asthmatics of any age.

Original languageEnglish (US)
Pages (from-to)322-326
Number of pages5
JournalAnnals of Emergency Medicine
Issue number4
StatePublished - Apr 1988


  • asthma, treatment, epinepherine
  • epinepherine, use asthma

ASJC Scopus subject areas

  • Emergency Medicine


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