The use of platelet-rich plasma for the treatment of osteoarthritis

Prakash Jayabalan, Sarah Hagerty, Megan Helen Cortazzo*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Osteoarthritis (OA) is the most common cause of disability in the United States. With an aging population, its incidence is only likely to rise. Articular cartilage has a poor capacity to heal. The advent of regenerative medicine has heralded a new approach to early treatment of degenerative conditions such as osteoarthritis by focusing on regenerating damaged tissue rather than focusing on replacement. Platelet-rich plasma (PRP) is one such treatment that has received much recent attention and has been used particularly for tendon healing. Recent studies have focused on assessing its use on degenerative conditions such as OA. In this article, we review the evidence for the pathologic basis for the use of PRP in OA and also the clinical outcomes pertaining to its use. Finally, we also consider reasons for the inconsistent clinical success pertaining to its use.

Original languageEnglish (US)
Pages (from-to)53-62
Number of pages10
JournalPhysician and Sportsmedicine
Issue number3
StatePublished - 2014


  • Degenerative joint disorder
  • Intra-articular pathology
  • Osteoarthritis
  • Platelet-rich plasma

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation


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