The validity of self-reported drug use in non-treatment seeking individuals with cocaine dependence: Correlation with biochemical assays

I. Elman; S. Krause; H. C. Breiter; R. L. Gollub; J. Heintges; W. A. Baumgartner; B. R. Rosen; D. R. Gastfriend

doi:10.1080/10550490050148044

The validity of self-reported drug use in non-treatment seeking individuals with cocaine dependence: Correlation with biochemical assays

I. Elman, S. Krause, H. C. Breiter, R. L. Gollub, J. Heintges, W. A. Baumgartner, B. R. Rosen, D. R. Gastfriend

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Accurate estimate of drug exposure plays an important role in studies of the neurobiology of drug dependence. The validity of self-reported drug use by subjects participating in such studies has not been well established. This study examined the relationship between self-reported drug use and biological markers in 18 non-treatment-seeking cocaine-dependent individuals participating in research on the effects of cocaine on the brain. A significant relationship was found between self-reported frequency of cocaine use and hair cocaine concentration. Frequency of alcohol use correlated significantly with plasma carbohydrate-deficient transferrin and aspartate aminotransferase levels. These results suggest that self-reported substance use in non-treatment seeking research subjects is generally valid.

Original language	English (US)
Pages (from-to)	216-221
Number of pages	6
Journal	American Journal on Addictions
Volume	9
Issue number	3
DOIs	https://doi.org/10.1080/10550490050148044
State	Published - 2000

ASJC Scopus subject areas

Medicine (miscellaneous)
Clinical Psychology
Psychiatry and Mental health

UN SDGs

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10.1080/10550490050148044

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AU - Krause, S.

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AU - Gollub, R. L.

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AU - Rosen, B. R.

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The validity of self-reported drug use in non-treatment seeking individuals with cocaine dependence: Correlation with biochemical assays

Abstract

ASJC Scopus subject areas

UN SDGs

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