Therapy of scleritis with cytotoxic agents

Lee M. Jampol*, Carole West, Morton F. Goldberg

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Four patients with severe anterior scleritis that had not responded to conventional therapy were treated with cytotoxic immunosuppressive alkylating agents alone (one case) or in combination with prednisone (three cases). Two of the patients had Wegener's granulomatosis, one pyoderma gangrenosum, and one rheumatoid vasculitis. All patients responded well to this therapy with a decrease in inflammation and a healing of the sclera. Other systemic manifestations of the underlying diseases often responded well also.

Original languageEnglish (US)
Pages (from-to)266-271
Number of pages6
Issue number2
StatePublished - Aug 1978

ASJC Scopus subject areas

  • Ophthalmology


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