TY - JOUR
T1 - Thoracic Manifestations of Rheumatoid Arthritis
AU - Esposito, Anthony J.
AU - Chu, Sarah G.
AU - Madan, Rachna
AU - Doyle, Tracy J.
AU - Dellaripa, Paul F.
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/9
Y1 - 2019/9
N2 - Rheumatoid arthritis (RA) is commonly associated with pulmonary disease that can affect any anatomic compartment of the thorax. The most common intrathoracic manifestations of RA include interstitial lung disease, airway disease, pleural disease, rheumatoid nodules, and drug-induced toxicity. Patients with RA with thoracic involvement often present with nonspecific respiratory symptoms, although many are asymptomatic. Therefore, clinicians should routinely consider pulmonary disease when evaluating any patient with RA, particularly one with known risk factors. The optimal screening, diagnostic, and treatment strategies for RA-associated pulmonary disease remain uncertain and are the focus of ongoing investigation.
AB - Rheumatoid arthritis (RA) is commonly associated with pulmonary disease that can affect any anatomic compartment of the thorax. The most common intrathoracic manifestations of RA include interstitial lung disease, airway disease, pleural disease, rheumatoid nodules, and drug-induced toxicity. Patients with RA with thoracic involvement often present with nonspecific respiratory symptoms, although many are asymptomatic. Therefore, clinicians should routinely consider pulmonary disease when evaluating any patient with RA, particularly one with known risk factors. The optimal screening, diagnostic, and treatment strategies for RA-associated pulmonary disease remain uncertain and are the focus of ongoing investigation.
KW - Bronchiectasis
KW - Bronchiolitis
KW - Drug-induced lung toxicity
KW - Rheumatoid arthritis
KW - Rheumatoid arthritis–associated interstitial lung disease
KW - Rheumatoid nodule
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U2 - 10.1016/j.ccm.2019.05.003
DO - 10.1016/j.ccm.2019.05.003
M3 - Review article
C2 - 31376890
AN - SCOPUS:85068476958
SN - 0272-5231
VL - 40
SP - 545
EP - 560
JO - Clinics in Chest Medicine
JF - Clinics in Chest Medicine
IS - 3
ER -