Thoracic Manifestations of Rheumatoid Arthritis

Anthony J. Esposito, Sarah G. Chu, Rachna Madan, Tracy J. Doyle, Paul F. Dellaripa*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations


Rheumatoid arthritis (RA) is commonly associated with pulmonary disease that can affect any anatomic compartment of the thorax. The most common intrathoracic manifestations of RA include interstitial lung disease, airway disease, pleural disease, rheumatoid nodules, and drug-induced toxicity. Patients with RA with thoracic involvement often present with nonspecific respiratory symptoms, although many are asymptomatic. Therefore, clinicians should routinely consider pulmonary disease when evaluating any patient with RA, particularly one with known risk factors. The optimal screening, diagnostic, and treatment strategies for RA-associated pulmonary disease remain uncertain and are the focus of ongoing investigation.

Original languageEnglish (US)
Pages (from-to)545-560
Number of pages16
JournalClinics in Chest Medicine
Issue number3
StatePublished - Sep 2019


  • Bronchiectasis
  • Bronchiolitis
  • Drug-induced lung toxicity
  • Rheumatoid arthritis
  • Rheumatoid arthritis–associated interstitial lung disease
  • Rheumatoid nodule

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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