Three-dimensional photoacoustic imaging of subcutaneous microvasculature in vivo

Hao F. Zhang*, Meng Lin Li, Konstantin Maslov, George Stoica, Lihong V. Wang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Three-dimensional photoacoustic imaging of subcutaneous microvasculature in small animals is realized in vivo using photoacoustic microscopy. Previously, degraded lateral resolution in the out-of-focus region made three-dimensional visualization impractical. With the help of a virtual-detector synthetic aperture focusing technique, depth-independent lateral resolution is achieved. Therefore, volumetric imaging of the vessels is realized with a lateral resolution of 45 μm and an axial resolution of 15 μm. Detailed structural information, such as vessel depth and spatial orientation, are revealed with new clarity.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
DOIs
StatePublished - 2006
Event7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006 - San Jose, CA, United States
Duration: Jan 22 2006Jan 26 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume6086
ISSN (Print)0277-786X

Other

Other7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006
CountryUnited States
CitySan Jose, CA
Period1/22/061/26/06

Keywords

  • Microscopy
  • Microvasculature
  • Photoacoustic

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Three-dimensional photoacoustic imaging of subcutaneous microvasculature in vivo'. Together they form a unique fingerprint.

Cite this