TY - CHAP
T1 - Thrombocytopenia and cancer
AU - Eklund, Elizabeth A.
PY - 2009
Y1 - 2009
N2 - Thrombocytopenia is frequently encountered in patients with solid tumors or hematologic malignancies. In these patients, it may be related to the underlying disease or it may be a consequence of treatment. In some cases, thrombocytopenia may be an isolated hematologic defect. However, thrombocytopenia in cancer patients will often be accompanied by variable amounts of anemia and/or neutropenia. In the majority of cases, thrombocytopenia in cancer patients is not clinically significant, but is discovered during routine blood counts. However, some of the causes of thrombocytopenia indicate the development of serious disorders which should be addressed promptly. Since the etiology of thrombocytopenia in cancer patients may be multifactorial, diagnosis is often complex. The main causes of thrombocytopenia are increased platelet destruction and decreased platelet production. Less frequent are splenic sequestration and dilutional thrombocytopenia.
AB - Thrombocytopenia is frequently encountered in patients with solid tumors or hematologic malignancies. In these patients, it may be related to the underlying disease or it may be a consequence of treatment. In some cases, thrombocytopenia may be an isolated hematologic defect. However, thrombocytopenia in cancer patients will often be accompanied by variable amounts of anemia and/or neutropenia. In the majority of cases, thrombocytopenia in cancer patients is not clinically significant, but is discovered during routine blood counts. However, some of the causes of thrombocytopenia indicate the development of serious disorders which should be addressed promptly. Since the etiology of thrombocytopenia in cancer patients may be multifactorial, diagnosis is often complex. The main causes of thrombocytopenia are increased platelet destruction and decreased platelet production. Less frequent are splenic sequestration and dilutional thrombocytopenia.
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U2 - 10.1007/978-0-387-79962-9_16
DO - 10.1007/978-0-387-79962-9_16
M3 - Chapter
C2 - 19377930
AN - SCOPUS:77953676857
SN - 9780387799612
T3 - Cancer Treatment and Research
SP - 279
EP - 293
BT - Coagulation in Cancer
A2 - Green, David
A2 - Kwaan, Hau
ER -