Thrombocytopenia in older adults

Brandon J. McMahon, Hau C. Kwaan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Thrombocytopenia in older patients is associated with several characteristics that are often underrecognized. Among them are the risk of bleeding complications, the senescence of the bone marrow, the increased use of multiple drugs, and greater comorbidity. In this article, the various forms of thrombocytopenia, including primary and drug-associated immune thrombocytopenias, as well as other drug-associated thrombocytopenias, are reviewed. In addition, how age-related changes in platelet function may affect the bleeding risk is discussed.

Original languageEnglish (US)
Pages (from-to)682-687
Number of pages6
JournalSeminars in Thrombosis and Hemostasis
Issue number6
StatePublished - Sep 1 2014


  • bleeding
  • drug-induced thrombocytopenia
  • immune thrombocytopenic purpura
  • older adults
  • thrombocytopenia

ASJC Scopus subject areas

  • Hematology
  • Cardiology and Cardiovascular Medicine


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