Thyroid hormone and bone

Peter A. Lakatos, Bence Bakos, Istvan Takacs, Paula H. Stern

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Thyroid hormone is essential for skeletal development and also affects mature bone. Depending on the hormone concentration and stage of life, the effects of thyroid hormone can be either beneficial or deleterious to the skeleton. This chapter focuses on the intracellular and cellular effects of thyroid hormone on bone cells as well as its relationship to the observed effects of the hormone on the skeleton in vivo in both experimental animals and humans. Studies published since the previous edition provide information on thyroid hormone effects on additional genes of interest in osteoblasts and further assessment of the skeletal risks of excess thyroid hormone.

Original languageEnglish (US)
Title of host publicationPrinciples of Bone Biology
PublisherElsevier
Pages895-914
Number of pages20
ISBN (Electronic)9780128148419
DOIs
StatePublished - Jan 1 2019

Keywords

  • Bone
  • Hormone
  • Osteoblasts
  • Osteoporosis
  • Thyroid
  • Thyroid hormon

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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  • Cite this

    Lakatos, P. A., Bakos, B., Takacs, I., & Stern, P. H. (2019). Thyroid hormone and bone. In Principles of Bone Biology (pp. 895-914). Elsevier. https://doi.org/10.1016/B978-0-12-814841-9.00038-5