Thyroid Medullary Carcinoma and Absent Histamine Flare

L. M. Jampol; V. L. Jacson

doi:10.1056/NEJM197203232861220

Thyroid Medullary Carcinoma and Absent Histamine Flare

L. M. Jampol, V. L. Jacson

Ophthalmology

Research output: Contribution to journal › Letter

2 Scopus citations

Abstract

To the Editor: A case report in the Journal (N Engl J Med 284:963–964, 1971) described a patient with multiple neurofibromas, metastatic medullary carcinoma of the thyroid gland, bilateral pheochromocytomas and the characteristic physical appearance of this syndrome. Dr. Baum, in addition, noted absence of a flare response to intradermal histamine, ectopic lacrimal puncta, an abnormal Schirmer tests. A letter in the Journal (N Engl J Med 284:983, 1971) by Gorlin confirmed the absence of the flare response in patients with thyroid medullary carcinoma, probably because of elevated histaminase levels. We have been following a 16-year-old boy with the syndrome ….

Original language	English (US)
Number of pages	1
Journal	New England Journal of Medicine
Volume	286
Issue number	12
DOIs	https://doi.org/10.1056/NEJM197203232861220
Publication status	Published - Mar 23 1972

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ASJC Scopus subject areas

Medicine(all)

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Jampol, L. M., & Jacson, V. L. (1972). Thyroid Medullary Carcinoma and Absent Histamine Flare. New England Journal of Medicine, 286(12). https://doi.org/10.1056/NEJM197203232861220

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10.1056/NEJM197203232861220