Abstract
To the Editor: A case report in the Journal (N Engl J Med 284:963–964, 1971) described a patient with multiple neurofibromas, metastatic medullary carcinoma of the thyroid gland, bilateral pheochromocytomas and the characteristic physical appearance of this syndrome. Dr. Baum, in addition, noted absence of a flare response to intradermal histamine, ectopic lacrimal puncta, an abnormal Schirmer tests. A letter in the Journal (N Engl J Med 284:983, 1971) by Gorlin confirmed the absence of the flare response in patients with thyroid medullary carcinoma, probably because of elevated histaminase levels. We have been following a 16-year-old boy with the syndrome ….
| Original language | English (US) |
|---|---|
| Number of pages | 1 |
| Journal | New England Journal of Medicine |
| Volume | 286 |
| Issue number | 12 |
| DOIs | |
| State | Published - Mar 23 1972 |
ASJC Scopus subject areas
- Medicine(all)
Fingerprint Dive into the research topics of 'Thyroid Medullary Carcinoma and Absent Histamine Flare'. Together they form a unique fingerprint.
Cite this
Jampol, L. M., & Jacson, V. L. (1972). Thyroid Medullary Carcinoma and Absent Histamine Flare. New England Journal of Medicine, 286(12). https://doi.org/10.1056/NEJM197203232861220