Tight Regulation of Circulating 1α,25-Dihydroxyvitamin D in Black Children

N. H. Bell, P. H. Stern, S. K. Paulson

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To the Editor: We have demonstrated previously that, after challenge with vitamin D, circulating 1α,25-dihydroxyvitamin D is loosely regulated in normal white children and tightly regulated in normal white adults.1,2 Thus, whereas mean serum 25-hydroxyvitamin D and mean serum 1α,25-dihydroxyvitamin D increased significantly in the white children, mean serum 25-hydroxyvitamin D increased significantly and mean serum 1α,25-dihydroxyvitamin D did not change in the white adults, in response to vitamin D. In the light of these results, we conducted studies to determine the effects of vitamin D in normal black children. Thirteen white children — seven boys and six girls.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Issue number22
StatePublished - Nov 28 1985


ASJC Scopus subject areas

  • Medicine(all)

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