Time course of changes in neuromuscular properties following stroke

M. M. Mirbagheri, C. Tsao, K. Settle, T. Lilaonitkul, W. Z. Rymer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Scopus citations

Abstract

To characterize the natural history of stroke effects on neuromuscular properties in elbow muscles, we tracked changes in elbow mechanical properties in hemiparetic stroke survivors after stroke. Using a parallel cascade system identification technique, we estimated intrinsic and reflex mechanical properties at 1, 2, 3, 6 and 12 months post stroke. At each time point, we examined neuromuscular changes during variations in mean elbow joint angle. Modulation of intrinsic and reflex properties was assessed using small amplitude pseudorandom positional perturbations at different mean elbow angles, over the entire range of motion. We identified two patterns of stroke effects on neuromuscular properties. In Group 1, intrinsic stiffness increased continuously after the stroke. In Group 2, it decreased continuously over this interval. Analogous results were recorded for reflex stiffness. These different recovery patterns may reflect the simultaneous emergence of two opposing mechanisms; i.e. brain recovery and secondary effects on neuromuscular properties. It follows that the progress of recovery may not reflect a single mechanism, and could depend on which mechanism is dominant at each time point.

Original languageEnglish (US)
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PublisherIEEE Computer Society
Pages5097-5100
Number of pages4
ISBN (Print)9781424418152
DOIs
StatePublished - Jan 1 2008
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: Aug 20 2008Aug 25 2008

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period8/20/088/25/08

Keywords

  • Elbow
  • Intrinsic
  • Reflex
  • Spasticity
  • Stiffness
  • Stroke
  • Time course

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

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