Time-course relationships between serum LH, serum progesterone and urinary pregnanediol concentrations in normal women

S. M. Judge*, J. P. Quade, W. S M Arrata, R. T. Chatterton

*Corresponding author for this work

Research output: Contribution to journalArticle

10 Scopus citations


A specific and sensitive gas Chromatographic method was used to investigate the concentration of pregnanediol glucuronide in urine in relation to the time of ovulation. Serum LH and progesterone concentrations in the same subjects were used as evidence for the occurrence of ovulation. The urinary concentration of pregnanediol glucuronide in 24-hour collections and in overnight specimens increased 2-fold or more from the day of the midcycle LH peak to the time of predicted ovulation (24-48 hour after the LH peak) in parallel with the rise in serum progesterone concentration.

Original languageEnglish (US)
Pages (from-to)175-187
Number of pages13
Issue number2
StatePublished - Feb 1978


ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Endocrinology
  • Pharmacology
  • Clinical Biochemistry
  • Organic Chemistry

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