Timing of meals: When is as critical as what and how much

Peng Jiang*, Fred W. Turek

*Corresponding author for this work

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Over the past decade, a large body of literature has demonstrated that disruptions of the endogenous circadian clock, whether environmental or genetic, lead to metabolic dysfunctions that are associated with obesity, diabetes, and other metabolic disorders. The phrase, “It is not only what you eat and how much you eat, but also when you eat” sends a simple message about circadian timing and body weight regulation. Communicating this message to clinicians and patients, while also elucidating the neuroendocrine, molecular, and genetic mechanisms underlying this phrase is essential to embrace the growing knowledge of the circadian impact on metabolism as a part of healthy life style as well as to incorporate it into clinical practice for improvement of overall human health. In this review, we discuss findings from animal models, as well as epidemiological and clinical studies in humans, which collectively promote the awareness of the role of circadian clock in metabolic functions and dysfunctions.

Original languageEnglish (US)
Pages (from-to)E369-E380
JournalAmerican Journal of Physiology - Endocrinology and Metabolism
Volume312
Issue number5
DOIs
StatePublished - May 2017

Keywords

  • Circadian clock
  • Metabolism
  • Obesity

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Physiology (medical)

Fingerprint Dive into the research topics of 'Timing of meals: When is as critical as what and how much'. Together they form a unique fingerprint.

  • Cite this