Tin level requirements for multiple gated studies in humans: A new perspective

Stephen M. Karesh*, Gary L. Dillehay, Robert E. Henkin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Stannous pyrophosphate (Sn-PYP) has been used for over a decade for in vivo and in vitro labeling of red blood cells with 99mTc. Literature references indicate minimum levels of stannous ion [Sn(II)] acceptable for successful labeling, based on in vitro experiments, to range from 140 to 400 ng/mL of whole blood. Our study was undertaken in 200 patients using two different commercially available formulations of Sn-PYP in order to quantitate the Sn(II) levels required on an in vivo basis to achieve consistently high quality labeling.

Original languageEnglish (US)
JournalInternational Journal of Radiation Applications and Instrumentation.
Volume13
Issue number6
DOIs
StatePublished - Jan 1 1986

ASJC Scopus subject areas

  • Medicine(all)

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