Abstract
Tip-enhanced Raman spectroscopy (TERS) is a powerful technique that integrates the vibrational fingerprinting of Raman spectroscopy and the sub-nanometer resolution of scanning probe microscopy (SPM). As a result, TERS is capable of obtaining chemical maps of analyzed specimens with exceptional lateral resolution. This is extremely valuable for the study of interactions between molecules and substrates, in addition to structural characterization of biological objects, such as viruses and amyloid fibrils, 2D polymeric materials, and monitoring electrochemical and photo-catalytic processes. In this mini-review, we discuss the most significant advances of TERS, including: super high resolution chemical imaging, monitoring of catalytic processes, incorporation of pulsed-excitation techniques, single-site electrochemistry, biosensing, and art conservation. We begin with a short overview of TERS, comparing it with other surface analytical techniques, followed by an overview of recent developments and future applications in TERS.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 16-24 |
| Number of pages | 9 |
| Journal | Chemical Physics Letters |
| Volume | 659 |
| DOIs | |
| State | Published - Aug 16 2016 |
Funding
E.A.P. and R.P.V.D. acknowledge support from the National Science Foundation Center for Chemical Innovation dedicated to Chemistry at the Space-Time Limit (CaSTL) Grant CHE-1414466 . D.K. and R.P.V.D were supported by the Air Force Office of Scientific Research MURI ( FA9550-14-1-0003 ). N.J., N.C., M.C.H. and R.P.V.D. acknowledge funding from the Department of Energy Office of Basic Energy Sciences (SISGR Grant DE-FG02-09ER16109 ). E.A.P., M.C.H., and R.P.V.D. also acknowledge support from the National Science Foundation Materials Research Science and Engineering Center ( DMR-1121262 ). E.A.P. was additionally supported by the National Science Foundation Graduate Research Fellowship under Grant DGE-1324585 . Mark C. Hersam is the Walter P. Murphy Professor of Materials Science and Engineering and Director of the Materials Research Center at Northwestern University. He earned a B.S. in Electrical Engineering from the University of Illinois at Urbana-Champaign (UIUC) in 1996, M.Phil. in Physics from the University of Cambridge in 1997, and Ph.D. in Electrical Engineering from UIUC in 2000. His research interests include nanofabrication, scanning probe microscopy, semiconductor surfaces, and nanoelectronic materials. His work has been recognized with several awards including a Presidential Early Career Award for Scientists and Engineers and a MacArthur Fellowship.
ASJC Scopus subject areas
- General Physics and Astronomy
- Physical and Theoretical Chemistry