Tissue cutting with microserrated biopsy punches

Marco Giovannini, Huaqing Ren, Xingsheng Wang, Kornel Ehmann

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


This paper investigates the application of bioinspired serrated cutting edges in tissue cutting by biopsy punches (BPs) to reduce the insertion force. BPs are frequently used as a diagnostic tool in many minimally invasive procedures, for both tissue extraction and the delivery of medical fluids. The proposed work is inspired by the mosquito's maxilla that features microserrations on its cutting edges with the purpose of painlessly puncturing the human skin. The objective of this paper is to study the application of maxillalike microserrations on commercial BPs. The fundamental goal is the minimization of the puncture force at the BP tip during insertion procedures. Microserrations were created on the cutting edge by using a picosecond laser while cutting tests were implemented on a customized testbed on phantom tissue. A reduction of 20-30% in the insertion forces has been achieved with microserrated punches with different texture depths encouraging, thereby, further studies and applications in biomedical devices. Three-dimensional (3D) and two-dimensional (2D) finite element simulations were also developed to investigate the impact of microserrated cutting edges on the stresses in the contact area during soft tissue cutting.

Original languageEnglish (US)
Article number041004
JournalJournal of Micro and Nano-Manufacturing
Issue number4
StatePublished - Dec 1 2017

ASJC Scopus subject areas

  • Mechanics of Materials
  • Process Chemistry and Technology
  • Industrial and Manufacturing Engineering


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