Tolerability and cosmetic acceptability of a body wash in atopic dermatitis-prone subjects

Staci Brandt*, Matthew H. Meckfessel, Peter A Lio

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Atopic dermatitis is a common skin disease characterized by eczematous eruptions and impaired skin barrier function. Patients, as well as their families, frequently report reductions in quality of life. Pruritus, lack of sleep, and impaired social functioning all contribute to this reduction. A skincare regimen of gentle cleansing and daily moisturization is integral to managing atopic dermatitis. While there are a multitude of reports supporting the use of moisturizers, there is a paucity regarding the use of cleansers, especially cleansers formulated with ingredients known to improve skin hydration. A clinical study was conducted to assess the tolerability and cosmetic acceptability of a body wash formulated with the filaggrin break-down products arginine and pyrrolidone carboxylic acid in subjects with atopic dermatitis-prone skin (Cetaphil® RestoraDerm® Body Wash). The results of this study indicate that Cetaphil RestoraDerm Body Wash was well tolerated, reduced itch, improved quality of life, and was well-liked by subjects with atopic dermatitis-prone skin.

Original languageEnglish (US)
Pages (from-to)1108-1111
Number of pages4
JournalJournal of Drugs in Dermatology
Volume13
Issue number9
StatePublished - Jan 1 2014

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Atopic Dermatitis
Cosmetics
Skin
Eczematous Skin Diseases
Quality of Life
Pyrrolidinones
Pruritus
Carboxylic Acids
Arginine
Sleep
cetyl alcohol, propylene glycol, sodium lauryl sulfate non-lipid cleansing lotion

ASJC Scopus subject areas

  • Dermatology
  • Medicine(all)

Cite this

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abstract = "Atopic dermatitis is a common skin disease characterized by eczematous eruptions and impaired skin barrier function. Patients, as well as their families, frequently report reductions in quality of life. Pruritus, lack of sleep, and impaired social functioning all contribute to this reduction. A skincare regimen of gentle cleansing and daily moisturization is integral to managing atopic dermatitis. While there are a multitude of reports supporting the use of moisturizers, there is a paucity regarding the use of cleansers, especially cleansers formulated with ingredients known to improve skin hydration. A clinical study was conducted to assess the tolerability and cosmetic acceptability of a body wash formulated with the filaggrin break-down products arginine and pyrrolidone carboxylic acid in subjects with atopic dermatitis-prone skin (Cetaphil{\circledR} RestoraDerm{\circledR} Body Wash). The results of this study indicate that Cetaphil RestoraDerm Body Wash was well tolerated, reduced itch, improved quality of life, and was well-liked by subjects with atopic dermatitis-prone skin.",
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Tolerability and cosmetic acceptability of a body wash in atopic dermatitis-prone subjects. / Brandt, Staci; Meckfessel, Matthew H.; Lio, Peter A.

In: Journal of Drugs in Dermatology, Vol. 13, No. 9, 01.01.2014, p. 1108-1111.

Research output: Contribution to journalArticle

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