Topiramate, pseudotumor cerebri, weight-loss and glaucoma: An ophthalmologic perspective

Patrick Alore; Walter Jay; Mícheál Macken

doi:10.1080/08820530500509325

Topiramate, pseudotumor cerebri, weight-loss and glaucoma: An ophthalmologic perspective

Patrick Alore, Walter Jay, Mícheál Macken^*

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Short survey › peer-review

23 Scopus citations

Abstract

Approved for the treatment of epilepsy and migraine prophylaxis, topiramate also acts as a carbonic anhydrase inhibitor implying a potential role in the treatment of pseudotumor cerebri (PTC). Topiramate has a propensity to cause anorexia with consequent weight loss, which alone may be curative in PTC. Prescribers must be aware of several reported cases of acute secondary angle-closure glaucoma reported in patients treated with topiramate.

Original language	English (US)
Pages (from-to)	15-17
Number of pages	3
Journal	Seminars in Ophthalmology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1080/08820530500509325
State	Published - Jan 1 2006

Keywords

Glaucoma
Pseudotumor cerebri
Topiramate
Weight loss

ASJC Scopus subject areas

Ophthalmology

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10.1080/08820530500509325

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AB - Approved for the treatment of epilepsy and migraine prophylaxis, topiramate also acts as a carbonic anhydrase inhibitor implying a potential role in the treatment of pseudotumor cerebri (PTC). Topiramate has a propensity to cause anorexia with consequent weight loss, which alone may be curative in PTC. Prescribers must be aware of several reported cases of acute secondary angle-closure glaucoma reported in patients treated with topiramate.

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