Topographic mapping of human motor cortex with transcranial magnetic stimulation: Homunculus revisited

Leo Verhagen Metman; Jacqueline S. Bellevich; Seth M. Jones; Matt D. Barber; Leopold J. Streletz

doi:10.1007/BF01234122

Topographic mapping of human motor cortex with transcranial magnetic stimulation: Homunculus revisited

Leo Verhagen Metman, Jacqueline S. Bellevich, Seth M. Jones, Matt D. Barber, Leopold J. Streletz^*

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

The purpose of this study was to non-invasively evaluate the homuncular organization of the motor cortex in man. We used transcranial magnetic stimulation to induce motor evoked potentials (MEP's) in Abductor Pollicis Brevis (APB) and Biceps Brachii (BB) muscles of 10 healthy volunteers. The practicality and accuracy of magnetic stimulation to scalp sites one cm apart was increased by the application to the scalp of a flexible nylon grid with grid size of 1×1 cm. Responsive scalp sites collectively contributed to distinct but overlapping muscle representational areas for the two muscles. The topography of these motor maps along and slightly anterior to the central fissure corresponds to the homuncular configuration as described by Penfield and Boldrey in 1937.

Original language	English (US)
Pages (from-to)	13-19
Number of pages	7
Journal	Brain Topography
Volume	6
Issue number	1
DOIs	https://doi.org/10.1007/BF01234122
State	Published - Sep 1993

Keywords

Homunculus
Human motor cortex
Motor Evoked Potential
Topographical map
Transcranial Magnetic Stimulation

ASJC Scopus subject areas

Anatomy
Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging
Neurology
Clinical Neurology

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10.1007/BF01234122

Cite this

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abstract = "The purpose of this study was to non-invasively evaluate the homuncular organization of the motor cortex in man. We used transcranial magnetic stimulation to induce motor evoked potentials (MEP's) in Abductor Pollicis Brevis (APB) and Biceps Brachii (BB) muscles of 10 healthy volunteers. The practicality and accuracy of magnetic stimulation to scalp sites one cm apart was increased by the application to the scalp of a flexible nylon grid with grid size of 1×1 cm. Responsive scalp sites collectively contributed to distinct but overlapping muscle representational areas for the two muscles. The topography of these motor maps along and slightly anterior to the central fissure corresponds to the homuncular configuration as described by Penfield and Boldrey in 1937.",

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AU - Barber, Matt D.

AU - Streletz, Leopold J.

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Topographic mapping of human motor cortex with transcranial magnetic stimulation: Homunculus revisited

Abstract

Keywords

ASJC Scopus subject areas

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