TY - JOUR
T1 - Total-Body PET/CT Applications in Cardiovascular Diseases
T2 - A Perspective Document of the SNMMI Cardiovascular Council
AU - Slart, Riemer H.J.A.
AU - Bengel, Frank M.
AU - Akincioglu, Cigdem
AU - Bourque, Jamieson M.
AU - Chen, Wengen
AU - Dweck, Marc R.
AU - Hacker, Marcus
AU - Malhotra, Saurabh
AU - Miller, Edward J.
AU - Pelletier-Galarneau, Matthieu
AU - Packard, René R.S.
AU - Schindler, Thomas H.
AU - Weinberg, Richard L.
AU - Saraste, Antti
AU - Slomka, Piotr J.
N1 - Publisher Copyright:
© 2024 by the Society of Nuclear Medicine andMolecular Imaging.
PY - 2024
Y1 - 2024
N2 - Digital PET/CT systems with a long axial field of view have become available and are emerging as the current state of the art. These new camera systems provide wider anatomic coverage, leading to major increases in system sensitivity. Preliminary results have demonstrated improvements in image quality and quantification, as well as substantial advantages in tracer kinetic modeling from dynamic imaging. These systems also potentially allow for low-dose examinations and major reductions in acquisition time. Thereby, they hold great promise to improve PET-based interrogation of cardiac physiology and biology. Additionally, the whole-body coverage enables simultaneous assessment of multiple organs and the large vascular structures of the body, opening new opportunities for imaging systemic mechanisms, disorders, or treatments and their interactions with the cardiovascular system as a whole. The aim of this perspective document is to debate the potential applications, challenges, opportunities, and remaining challenges of applying PET/CT with a long axial field of view to the field of cardiovascular disease.
AB - Digital PET/CT systems with a long axial field of view have become available and are emerging as the current state of the art. These new camera systems provide wider anatomic coverage, leading to major increases in system sensitivity. Preliminary results have demonstrated improvements in image quality and quantification, as well as substantial advantages in tracer kinetic modeling from dynamic imaging. These systems also potentially allow for low-dose examinations and major reductions in acquisition time. Thereby, they hold great promise to improve PET-based interrogation of cardiac physiology and biology. Additionally, the whole-body coverage enables simultaneous assessment of multiple organs and the large vascular structures of the body, opening new opportunities for imaging systemic mechanisms, disorders, or treatments and their interactions with the cardiovascular system as a whole. The aim of this perspective document is to debate the potential applications, challenges, opportunities, and remaining challenges of applying PET/CT with a long axial field of view to the field of cardiovascular disease.
KW - cardiovascular diseases
KW - current status
KW - future perspectives
KW - long axial field-of-view PET/CT
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U2 - 10.2967/jnumed.123.266858
DO - 10.2967/jnumed.123.266858
M3 - Article
C2 - 38388512
AN - SCOPUS:85189199687
SN - 0161-5505
VL - 65
SP - 607
EP - 616
JO - Journal of Nuclear Medicine
JF - Journal of Nuclear Medicine
IS - 4
ER -
