Abstract
A tale of two Michaels: The first enantioselective total synthesis of (-)-GB17 is reported. Construction of this unique naphthoquinolizinone skeleton was achieved by two stereoselective intramolecular Michael additions, one under catalyst control and the other under substrate control.
Original language | English (US) |
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Pages (from-to) | 2481-2484 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 51 |
Issue number | 10 |
DOIs | |
State | Published - Mar 5 2012 |
Keywords
- Galbulimima alkaloids
- Michael addition
- natural product synthesis
- organocatalysis
- substrate control
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)