Toward a deeper understanding of gene-by-sex interaction models

Ekaterina A. Khramtsova, Stacey J. Winham, Lea K. Davis, Barbara E. Stranger, Melissa A. Wilson*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

2 Scopus citations

Abstract

In this issue of Cell Genomics, Zhu et al.1 propose amplification as the primary mode for gene-by-sex interactions in complex traits. Khramtsova et al. preview their modeling approach and discuss implications for the future work on the genomics of sex differences.

Original languageEnglish (US)
Article number100324
JournalCell Genomics
Volume3
Issue number5
DOIs
StatePublished - May 10 2023

Funding

M.A.W. was supported by the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH) grant R35GM124827. B.E.S. was supported by NIH grant R01 CA229618. L.K.D. and B.E.S. were supported by NIH grant R01 HG011405. E.A.K. is an employee of Janssen Pharmaceutical Companies of Johnson & Johnson. M.A.W. was supported by the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health ( NIH ) grant R35GM124827 . B.E.S. was supported by NIH grant R01 CA229618 . L.K.D. and B.E.S. were supported by NIH grant R01 HG011405 .

ASJC Scopus subject areas

  • Genetics
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)

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