Tracking RNA structures as RNAs transit through the cell

Angela M. Yu; Julius B. Lucks

doi:10.1038/s41594-019-0213-2

Tracking RNA structures as RNAs transit through the cell

Angela M. Yu, Julius B. Lucks^*

^*Corresponding author for this work

Chemical and Biological Engineering

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

RNAs perform diverse cellular functions that are mediated at least in part by their structure. However, how RNA structure changes throughout the RNA lifecycle and how these changes affect RNA function remain incompletely understood. A detailed in vivo characterization of RNA structure in various cellular subcompartments now provides insights into how RNA structural changes influence translation, RNA decay, protein binding and RNA modification.

Original language	English (US)
Pages (from-to)	256-257
Number of pages	2
Journal	Nature Structural and Molecular Biology
Volume	26
Issue number	4
DOIs	https://doi.org/10.1038/s41594-019-0213-2
State	Published - Apr 1 2019

ASJC Scopus subject areas

Molecular Biology
Structural Biology

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title = "Tracking RNA structures as RNAs transit through the cell",

abstract = "RNAs perform diverse cellular functions that are mediated at least in part by their structure. However, how RNA structure changes throughout the RNA lifecycle and how these changes affect RNA function remain incompletely understood. A detailed in vivo characterization of RNA structure in various cellular subcompartments now provides insights into how RNA structural changes influence translation, RNA decay, protein binding and RNA modification.",

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AB - RNAs perform diverse cellular functions that are mediated at least in part by their structure. However, how RNA structure changes throughout the RNA lifecycle and how these changes affect RNA function remain incompletely understood. A detailed in vivo characterization of RNA structure in various cellular subcompartments now provides insights into how RNA structural changes influence translation, RNA decay, protein binding and RNA modification.

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Tracking RNA structures as RNAs transit through the cell

Abstract

ASJC Scopus subject areas

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