Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia with regular ventricular tachycardia and response to flecainide

Mohammad A. Ebrahim; Ali A. Alkhabbaz; Buthaina Albash; Ali H. AlSayegh; Gregory Webster

doi:10.1111/jce.16011

Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia with regular ventricular tachycardia and response to flecainide

Mohammad A. Ebrahim^*, Ali A. Alkhabbaz, Buthaina Albash, Ali H. AlSayegh, Gregory Webster

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Introduction: We describe a unique case of TECRL-CPVT presented with cardiac arrest. Methods: Post resuscitation, the patient developed regular ventricular tachycardia featuring a left purkinje system morphology. Results: There was clear suppression of arrhythmia with the addition of flecainide and isolated ventricular ectopy causing secondary T-wave changes. Conclusion: A high index of suspicion was required to eventually make the diagnosis through whole exome sequencing.

Original language	English (US)
Pages (from-to)	1996-2001
Number of pages	6
Journal	Journal of cardiovascular electrophysiology
Volume	34
Issue number	9
DOIs	https://doi.org/10.1111/jce.16011
State	Published - Sep 2023

Keywords

CPVT
TECRL
cardiac arrest

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

Access to Document

10.1111/jce.16011

Cite this

@article{05239f77e7344fcc8630b9d706810fbd,

title = "Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia with regular ventricular tachycardia and response to flecainide",

abstract = "Introduction: We describe a unique case of TECRL-CPVT presented with cardiac arrest. Methods: Post resuscitation, the patient developed regular ventricular tachycardia featuring a left purkinje system morphology. Results: There was clear suppression of arrhythmia with the addition of flecainide and isolated ventricular ectopy causing secondary T-wave changes. Conclusion: A high index of suspicion was required to eventually make the diagnosis through whole exome sequencing.",

keywords = "CPVT, TECRL, cardiac arrest",

author = "Ebrahim, {Mohammad A.} and Alkhabbaz, {Ali A.} and Buthaina Albash and AlSayegh, {Ali H.} and Gregory Webster",

note = "Publisher Copyright: {\textcopyright} 2023 Wiley Periodicals LLC.",

year = "2023",

month = sep,

doi = "10.1111/jce.16011",

language = "English (US)",

volume = "34",

pages = "1996--2001",

journal = "Journal of cardiovascular electrophysiology",

issn = "1045-3873",

publisher = "Wiley-Blackwell",

number = "9",

}

Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia with regular ventricular tachycardia and response to flecainide. / Ebrahim, Mohammad A.; Alkhabbaz, Ali A.; Albash, Buthaina et al.
In: Journal of cardiovascular electrophysiology, Vol. 34, No. 9, 09.2023, p. 1996-2001.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia with regular ventricular tachycardia and response to flecainide

AU - Ebrahim, Mohammad A.

AU - Alkhabbaz, Ali A.

AU - Albash, Buthaina

AU - AlSayegh, Ali H.

AU - Webster, Gregory

PY - 2023/9

Y1 - 2023/9

N2 - Introduction: We describe a unique case of TECRL-CPVT presented with cardiac arrest. Methods: Post resuscitation, the patient developed regular ventricular tachycardia featuring a left purkinje system morphology. Results: There was clear suppression of arrhythmia with the addition of flecainide and isolated ventricular ectopy causing secondary T-wave changes. Conclusion: A high index of suspicion was required to eventually make the diagnosis through whole exome sequencing.

AB - Introduction: We describe a unique case of TECRL-CPVT presented with cardiac arrest. Methods: Post resuscitation, the patient developed regular ventricular tachycardia featuring a left purkinje system morphology. Results: There was clear suppression of arrhythmia with the addition of flecainide and isolated ventricular ectopy causing secondary T-wave changes. Conclusion: A high index of suspicion was required to eventually make the diagnosis through whole exome sequencing.

KW - CPVT

KW - TECRL

KW - cardiac arrest

UR - http://www.scopus.com/inward/record.url?scp=85165437249&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85165437249&partnerID=8YFLogxK

U2 - 10.1111/jce.16011

DO - 10.1111/jce.16011

M3 - Article

C2 - 37473425

AN - SCOPUS:85165437249

SN - 1045-3873

VL - 34

SP - 1996

EP - 2001

JO - Journal of cardiovascular electrophysiology

JF - Journal of cardiovascular electrophysiology

IS - 9

ER -

Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia with regular ventricular tachycardia and response to flecainide

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this