Transbronchial lung cryobiopsy for interstitial lung disease diagnosis: A perspective from members of the pulmonary pathology society

Kirtee Raparia, Dara L. Aisner, Timothy Craig Allen*, Mary Beth Beasley, Alain Borczuk, Philip T. Cagle, Vera Capelozzi, Sanja Dacic, Lida P. Hariri, Keith M. Kerr, Sylvie Lantuejoul, Mari Mino-Kenudson, Natasha Rekhtman, Anja C. Roden, Sinchita Roy-Chowdhuri, Lynette Sholl, Maxwell L. Smith, Eric Thunnissen, Ming Sound Tsao, Yasushi Yatabe

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Transbronchial lung cryobiopsy involves using a cryoprobe rather than forceps to obtain a bronchoscopic biopsy. Recent studies have shown that transbronchial cryobiopsy provides a larger specimen than conventional transbronchial forceps biopsy, and that the interobserver agreement in the interpretation of cryobiopsy specimens is comparable to that of a surgical lung biopsy. This is encouraging, and transbronchial lung cryobiopsy clearly has a role in the workup and diagnosis of interstitial lung diseases. However, very few patients who have been studied underwent both transbronchial lung cryobiopsy and surgical lung biopsy, and the available data suggest that the diagnostic accuracy of cryobiopsy may not be similar to that of surgical lung biopsy. Further study is needed before transbronchial lung biopsy can be recommended as a replacement for surgical lung biopsy.

Original languageEnglish (US)
Pages (from-to)1281-1284
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume140
Issue number11
DOIs
StatePublished - Nov 2016

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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