Transcription factors: positive and negative regulators of cell growth and disease

Richard I Morimoto*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Recent advances in our understanding of transcription factors that regulate RNA polymerase II transcribed genes are described. This review considers the role of alternate protein-protein interactions to yield positive or negative regulation, the consequences of deregulated factor activity on cell function and approaches to establish factor-binding specificities.

Original languageEnglish (US)
Pages (from-to)480-487
Number of pages8
JournalCurrent Opinion in Cell Biology
Volume4
Issue number3
DOIs
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • Cell Biology

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