Transcription factors: positive and negative regulators of cell growth and disease

Richard I Morimoto

doi:10.1016/0955-0674(92)90015-5

Transcription factors: positive and negative regulators of cell growth and disease

Richard I Morimoto^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Recent advances in our understanding of transcription factors that regulate RNA polymerase II transcribed genes are described. This review considers the role of alternate protein-protein interactions to yield positive or negative regulation, the consequences of deregulated factor activity on cell function and approaches to establish factor-binding specificities.

Original language	English (US)
Pages (from-to)	480-487
Number of pages	8
Journal	Current Opinion in Cell Biology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/0955-0674(92)90015-5
State	Published - Jan 1 1992

ASJC Scopus subject areas

Cell Biology

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title = "Transcription factors: positive and negative regulators of cell growth and disease",

abstract = "Recent advances in our understanding of transcription factors that regulate RNA polymerase II transcribed genes are described. This review considers the role of alternate protein-protein interactions to yield positive or negative regulation, the consequences of deregulated factor activity on cell function and approaches to establish factor-binding specificities.",

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