Transcriptional Memory: Staying in the Loop

Jason H. Brickner

doi:10.1016/j.cub.2009.11.013

Transcriptional Memory: Staying in the Loop

Jason H. Brickner^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Short survey › peer-review

17 Scopus citations

Abstract

Actively transcribed genes are organized into loops in which the 5′ and 3′ ends of the gene physically associate. Two new papers show that gene looping can persist after genes are repressed, promoting rapid reactivation of transcription, a phenomenon known as transcriptional memory.

Original language	English (US)
Pages (from-to)	R20-R21
Journal	Current Biology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/j.cub.2009.11.013
State	Published - Jan 12 2010

Funding

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

Access to Document

10.1016/j.cub.2009.11.013

Cite this

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abstract = "Actively transcribed genes are organized into loops in which the 5′ and 3′ ends of the gene physically associate. Two new papers show that gene looping can persist after genes are repressed, promoting rapid reactivation of transcription, a phenomenon known as transcriptional memory.",

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