Abstract
Transduction of stem cells with a marking gene holds promise to determine if tissue repair or regeneration is derived from the adult hematopoietic stem cell and if relapse of an autoimmune disease should occur whether relapse arises from the stem cell compartment or from lymphocytes surviving the conditioning regimen. New safety concerns about gene-modified stem cell would entail new safety testing such as documentation of the insertional site prior to release.
Original language | English (US) |
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Pages (from-to) | S33-S35 |
Journal | Bone Marrow Transplantation |
Volume | 32 |
DOIs | |
State | Published - Aug 2003 |
Externally published | Yes |
Keywords
- Autoimmune disease
- Gene transduction
- Stem cells
ASJC Scopus subject areas
- Transplantation
- Hematology