Abstract
The pathophysiologic basis for reduced fitness in sickle cell disease (SCD) is multifactorial and characterized by impaired oxygen-carrying capacity, derangements in the cardiopulmonary response to exercise, and abnormal metabolic responses in working muscles. In this issue of Blood, Merlet et al1 demonstrated in a provocative and elegant study that exercise training led to muscle capillary growth in people with SCD.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2227-2229 |
| Number of pages | 3 |
| Journal | Blood |
| Volume | 134 |
| Issue number | 25 |
| DOIs | |
| State | Published - Dec 19 2019 |
ASJC Scopus subject areas
- Hematology
- Biochemistry
- Cell Biology
- Immunology