Translating the Science of Psoriasis

Kenneth B. Gordon

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Knowledge about the pathophysiology of psoriasis has evolved substantially in recent years, since the identification of the T helper 17 (Th17) cells. Cytokines produced by these cells appear to play major roles in psoriatic inflammation. The cytokine interleukin (IL)-23 appears to promote regulatory T cells to differentiate into Th17 cells. Available and investigational therapies act on targets within these pathways.

Original languageEnglish (US)
JournalSeminars in cutaneous medicine and surgery
Issue number4 S
StatePublished - 2016


  • IL-17
  • IL-23
  • Psoriasis treatment
  • Th17 pathway

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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