Translating the Science of Psoriasis

Kenneth B. Gordon

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Knowledge about the pathophysiology of psoriasis has evolved substantially in recent years, since the identification of the T helper 17 (Th17) cells. Cytokines produced by these cells appear to play major roles in psoriatic inflammation. The cytokine interleukin (IL)-23 appears to promote regulatory T cells to differentiate into Th17 cells. Available and investigational therapies act on targets within these pathways.

Original languageEnglish (US)
JournalSeminars in cutaneous medicine and surgery
Volume35
Issue number4 S
DOIs
StatePublished - 2016

Funding

Publication of this CME/CE article was jointly provided by Rutgers, The State University of New Jersey and Global Academy for Medical Education, LLC with Skin Disease Education Foundation (SDEF) and is supported by educational grants from AbbVie Inc. and Novartis Pharmaceuticals Corporation.

Keywords

  • IL-17
  • IL-23
  • Psoriasis treatment
  • Th17 pathway

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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