Translating the Science of Psoriasis

Kenneth B. Gordon

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Knowledge about the pathophysiology of psoriasis has evolved substantially in recent years, since the identification of the T helper 17 (Th17) cells. Cytokines produced by these cells appear to play major roles in psoriatic inflammation. The cytokine interleukin (IL)-23 appears to promote regulatory T cells to differentiate into Th17 cells. Available and investigational therapies act on targets within these pathways.

Original languageEnglish (US)
Pages (from-to)S64
JournalSeminars in cutaneous medicine and surgery
Volume35
Issue number4
DOIs
StatePublished - Jun 1 2016

Keywords

  • IL-17
  • IL-23
  • Psoriasis treatment
  • Th17 pathway

ASJC Scopus subject areas

  • Surgery
  • Dermatology

Fingerprint

Dive into the research topics of 'Translating the Science of Psoriasis'. Together they form a unique fingerprint.

Cite this