TY - JOUR
T1 - Transplacental isopropanol exposure
T2 - Case report and review of metabolic principles
AU - Wood, J. N.
AU - Carney, J.
AU - Szczepanski, K.
AU - Calello, D. P.
AU - Hurt, H.
PY - 2007/3
Y1 - 2007/3
N2 - Isopropanol, a known central nervous system depressant has been reported to cause toxicity via multiple routes including ingestion, inhalation and dermal exposure. We present a case of transplacental isopropanol exposure in a neonate. A woman reported polysubstance abuse in the 1 to 2 days before precipitously delivering a newborn infant. The neonate developed hypotension, hypotonia and seizure activity within the first few hours of life. Blood samples from the infant revealed toxic levels of isopropanol. Similar symptoms have been reported in infants with isopropanol toxicity from other routes of exposure.
AB - Isopropanol, a known central nervous system depressant has been reported to cause toxicity via multiple routes including ingestion, inhalation and dermal exposure. We present a case of transplacental isopropanol exposure in a neonate. A woman reported polysubstance abuse in the 1 to 2 days before precipitously delivering a newborn infant. The neonate developed hypotension, hypotonia and seizure activity within the first few hours of life. Blood samples from the infant revealed toxic levels of isopropanol. Similar symptoms have been reported in infants with isopropanol toxicity from other routes of exposure.
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U2 - 10.1038/sj.jp.7211646
DO - 10.1038/sj.jp.7211646
M3 - Article
C2 - 17314988
AN - SCOPUS:33847334764
SN - 0743-8346
VL - 27
SP - 183
EP - 185
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 3
ER -