Treatment of brain metastases

Rimas V. Lukas; Patrik Gabikian; Madeline Garza; Steven J. Chmura

doi:10.1159/000362389

Treatment of brain metastases

Rimas V. Lukas, Patrik Gabikian, Madeline Garza, Steven J. Chmura

Neurology

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

Brain metastases are associated with substantial morbidity and mortality. Key prognostic classification systems for brain metastases are reviewed. The role of surgery, particularly for single brain metastases, is discussed. This is followed by an overview of radiation, both whole brain and focal, in the treatment of brain metastases. Finally, we review examples of important concepts regarding the role of systemic therapy in the treatment of brain metastases.

Original language	English
Pages (from-to)	321-329
Number of pages	9
Journal	Oncology (Switzerland)
Volume	87
Issue number	6
DOIs	https://doi.org/10.1159/000362389
State	Published - Apr 17 2014

Keywords

Bevacizumab
Brain
Brain metastases
Chemotherapy
Ipilimumab
Neoplasm metastasis
Neurosurgery
Radiosurgery
Radiotherapy
Temozolomide

ASJC Scopus subject areas

Cancer Research
Oncology
Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000362389

Cite this

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title = "Treatment of brain metastases",

abstract = "Brain metastases are associated with substantial morbidity and mortality. Key prognostic classification systems for brain metastases are reviewed. The role of surgery, particularly for single brain metastases, is discussed. This is followed by an overview of radiation, both whole brain and focal, in the treatment of brain metastases. Finally, we review examples of important concepts regarding the role of systemic therapy in the treatment of brain metastases.",

keywords = "Bevacizumab, Brain, Brain metastases, Chemotherapy, Ipilimumab, Neoplasm metastasis, Neurosurgery, Radiosurgery, Radiotherapy, Temozolomide",

author = "Lukas, {Rimas V.} and Patrik Gabikian and Madeline Garza and Chmura, {Steven J.}",

note = "Publisher Copyright: {\textcopyright} 2014 S. Karger AG, Basel.",

year = "2014",

month = apr,

day = "17",

doi = "10.1159/000362389",

language = "English",

volume = "87",

pages = "321--329",

journal = "Oncology",

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TY - JOUR

T1 - Treatment of brain metastases

AU - Lukas, Rimas V.

AU - Gabikian, Patrik

AU - Garza, Madeline

AU - Chmura, Steven J.

PY - 2014/4/17

Y1 - 2014/4/17

N2 - Brain metastases are associated with substantial morbidity and mortality. Key prognostic classification systems for brain metastases are reviewed. The role of surgery, particularly for single brain metastases, is discussed. This is followed by an overview of radiation, both whole brain and focal, in the treatment of brain metastases. Finally, we review examples of important concepts regarding the role of systemic therapy in the treatment of brain metastases.

AB - Brain metastases are associated with substantial morbidity and mortality. Key prognostic classification systems for brain metastases are reviewed. The role of surgery, particularly for single brain metastases, is discussed. This is followed by an overview of radiation, both whole brain and focal, in the treatment of brain metastases. Finally, we review examples of important concepts regarding the role of systemic therapy in the treatment of brain metastases.

KW - Bevacizumab

KW - Brain

KW - Brain metastases

KW - Chemotherapy

KW - Ipilimumab

KW - Neoplasm metastasis

KW - Neurosurgery

KW - Radiosurgery

KW - Radiotherapy

KW - Temozolomide

UR - http://www.scopus.com/inward/record.url?scp=84922394944&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922394944&partnerID=8YFLogxK

U2 - 10.1159/000362389

DO - 10.1159/000362389

M3 - Review article

C2 - 25227433

AN - SCOPUS:84922394944

SN - 0890-9091

VL - 87

SP - 321

EP - 329

JO - Oncology

JF - Oncology

IS - 6

ER -

Treatment of brain metastases

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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