Treatment of brain metastases

Rimas V. Lukas, Patrik Gabikian, Madeline Garza, Steven J. Chmura

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

Brain metastases are associated with substantial morbidity and mortality. Key prognostic classification systems for brain metastases are reviewed. The role of surgery, particularly for single brain metastases, is discussed. This is followed by an overview of radiation, both whole brain and focal, in the treatment of brain metastases. Finally, we review examples of important concepts regarding the role of systemic therapy in the treatment of brain metastases.

Original languageEnglish
Pages (from-to)321-329
Number of pages9
JournalOncology (Switzerland)
Volume87
Issue number6
DOIs
StatePublished - Apr 17 2014

Keywords

  • Bevacizumab
  • Brain
  • Brain metastases
  • Chemotherapy
  • Ipilimumab
  • Neoplasm metastasis
  • Neurosurgery
  • Radiosurgery
  • Radiotherapy
  • Temozolomide

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

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  • Cite this

    Lukas, R. V., Gabikian, P., Garza, M., & Chmura, S. J. (2014). Treatment of brain metastases. Oncology (Switzerland), 87(6), 321-329. https://doi.org/10.1159/000362389