Treatment of eosinophilic esophagus: Drugs, diet, or dilation?

Ameesh Shah, Ikuo Hirano*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

A number of recent studies have demonstrated that a variety of treatments effectively improve sypmtoms and histology in the majority of patients with eosinophilic esophagitis. Therapeutic options include pharmacologic treatments, such as oral and topical corticosteroids and leukotriene-receptor antagonists. In children, the high response rate to dietary modification and elimination suggest that certain foods may serve as environmental triggers fir the eosinophilic infiltration. Because many adults present with strictures, endoscopic esophageal dilation is another management modality. Despite these treatment options, several controversies exist in the recommended treatment strategy. Whether the goal of therapy is resolution of symptoms, tissue eosinophilia, or both remains uncertain owing to the paucity of data on the natural history of the condition. Furthermore, important differences in the clinical presentations of eosinophilic esophagitis in children and adults point toward the possible need for different treatment approaches in the two patient populations.

Original languageEnglish (US)
Pages (from-to)181-188
Number of pages8
JournalCurrent gastroenterology reports
Volume9
Issue number3
DOIs
StatePublished - Jun 1 2007

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint

Dive into the research topics of 'Treatment of eosinophilic esophagus: Drugs, diet, or dilation?'. Together they form a unique fingerprint.

Cite this