Treatment of Peripartum Bipolar Disorder

Crystal T. Clark*, Katherine L. Wisner

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


Bipolar disorder affects women throughout their childbearing years. During the perinatal period, women with bipolar disorder are vulnerable to depressive episode recurrences and have an increased risk for postpartum psychosis. Perinatal screening is critical to identify women at risk. Although medications are the mainstay of treatment, the choice of pharmacotherapy must be made by the patient based on a risk–benefit discussion with her physician. For optimal dosing in pregnancy, therapeutic drug monitoring may be required to maintain effective drug concentrations. Residual symptoms of bipolar depression are treatable with bright light therapy as an alternative to medication augmentation.

Original languageEnglish (US)
Pages (from-to)403-417
Number of pages15
JournalObstetrics and Gynecology Clinics of North America
Issue number3
StatePublished - Sep 2018


  • Antipsychotics
  • Bipolar disorder
  • Carbamazepine
  • Lamotrigine
  • Light therapy
  • Lithium
  • MDQ
  • Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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