Treatment of residual disease following neoadjuvant therapy in breast cancer

Natalie K. Heater, Khyati Somayaji, William Gradishar*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Substantial advances have been made in the systemic treatment of breast cancer with residual disease following neoadjuvant therapy. We reviewed recent and ongoing studies informing the standard clinical management of residual disease by subtype: HER2+, TNBC, and HR+/HER2-, as well as strategies for BRCA+ disease. We conclude with a discussion of ongoing clinical trials and current controversies regarding the treatment of residual disease in breast cancer.

Original languageEnglish (US)
Pages (from-to)18-25
Number of pages8
JournalJournal of surgical oncology
Volume129
Issue number1
DOIs
StatePublished - Jan 2024

Keywords

  • adjuvant therapy
  • breast cancer
  • postneoadjuvant
  • residual cancer burden
  • residual disease

ASJC Scopus subject areas

  • Surgery
  • Oncology

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