TY - JOUR
T1 - Treatment of schizophrenia
T2 - Preventing the progression of disease
AU - Csernansky, John G.
PY - 2003/1/1
Y1 - 2003/1/1
N2 - Atypical antipsychotic drugs offer a number of advantages compared with typical antipsychotic drugs during the acute treatment of psychotic episodes and maintenance treatment to prevent psychotic relapses in patients with schizophrenia. These advantages include superior efficacy, especially for negative symptoms and reduced extrapyramidal adverse effects. Clinicians, however, need to be vigilant regarding new adverse effects that may be more strongly associated with atypical than typical drugs, especially those related to weight gain. Despite increased pill costs for atypical antipsychotic drugs, the overall costs of providing care to patients with schizophrenia using these drugs do not appear to be substantially higher.
AB - Atypical antipsychotic drugs offer a number of advantages compared with typical antipsychotic drugs during the acute treatment of psychotic episodes and maintenance treatment to prevent psychotic relapses in patients with schizophrenia. These advantages include superior efficacy, especially for negative symptoms and reduced extrapyramidal adverse effects. Clinicians, however, need to be vigilant regarding new adverse effects that may be more strongly associated with atypical than typical drugs, especially those related to weight gain. Despite increased pill costs for atypical antipsychotic drugs, the overall costs of providing care to patients with schizophrenia using these drugs do not appear to be substantially higher.
UR - http://www.scopus.com/inward/record.url?scp=0037910073&partnerID=8YFLogxK
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U2 - 10.1016/S0193-953X(02)00113-2
DO - 10.1016/S0193-953X(02)00113-2
M3 - Review article
C2 - 12778839
AN - SCOPUS:0037910073
SN - 0193-953X
VL - 26
SP - 367
EP - 379
JO - Psychiatric Clinics of North America
JF - Psychiatric Clinics of North America
IS - 2
ER -