Treatment of schizophrenia: Preventing the progression of disease

John G. Csernansky*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Atypical antipsychotic drugs offer a number of advantages compared with typical antipsychotic drugs during the acute treatment of psychotic episodes and maintenance treatment to prevent psychotic relapses in patients with schizophrenia. These advantages include superior efficacy, especially for negative symptoms and reduced extrapyramidal adverse effects. Clinicians, however, need to be vigilant regarding new adverse effects that may be more strongly associated with atypical than typical drugs, especially those related to weight gain. Despite increased pill costs for atypical antipsychotic drugs, the overall costs of providing care to patients with schizophrenia using these drugs do not appear to be substantially higher.

Original languageEnglish (US)
Pages (from-to)367-379
Number of pages13
JournalPsychiatric Clinics of North America
Issue number2
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Psychiatry and Mental health


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