Treatment of stiff‐man syndrome with intravenous immune globulin

Elizabeth W. Karlson; Lewis Sudarsky; Eric Ruderman; Susan Pierson; Mary Scott; Simon M. Helfgott

doi:10.1002/art.1780370621

Treatment of stiff‐man syndrome with intravenous immune globulin

Elizabeth W. Karlson, Lewis Sudarsky, Eric Ruderman, Susan Pierson, Mary Scott, Simon M. Helfgott^*

^*Corresponding author for this work

Medicine, Rheumatology Division

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff‐man syndrome (SMS). Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids. Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function. Conclusion. IVIG may be useful for the treatment of SMS.

Original language	English (US)
Pages (from-to)	915-918
Number of pages	4
Journal	Arthritis & Rheumatism
Volume	37
Issue number	6
DOIs	https://doi.org/10.1002/art.1780370621
State	Published - Jun 1994

ASJC Scopus subject areas

Immunology and Allergy
Rheumatology
Immunology
Pharmacology (medical)

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title = "Treatment of stiff‐man syndrome with intravenous immune globulin",

abstract = "Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff‐man syndrome (SMS). Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids. Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function. Conclusion. IVIG may be useful for the treatment of SMS.",

author = "Karlson, {Elizabeth W.} and Lewis Sudarsky and Eric Ruderman and Susan Pierson and Mary Scott and Helfgott, {Simon M.}",

year = "1994",

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AU - Karlson, Elizabeth W.

AU - Sudarsky, Lewis

AU - Ruderman, Eric

AU - Pierson, Susan

AU - Scott, Mary

AU - Helfgott, Simon M.

PY - 1994/6

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N2 - Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff‐man syndrome (SMS). Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids. Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function. Conclusion. IVIG may be useful for the treatment of SMS.

AB - Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff‐man syndrome (SMS). Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids. Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function. Conclusion. IVIG may be useful for the treatment of SMS.

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