Trends in antimicrobial resistance of Acinetobacter baumannii isolates from a Metropolitan Detroit health system

Tara Reddy; Teena Chopra; Dror Marchaim; Jason M. Pogue; George Alangaden; Hossein Salimnia; Dina Boikov; Shiri Navon-Venezia; Robert Akins; Philip Selman; Sorabh Dhar; Keith S. Kaye

doi:10.1128/AAC.01665-09

Trends in antimicrobial resistance of Acinetobacter baumannii isolates from a Metropolitan Detroit health system

Tara Reddy^*, Teena Chopra, Dror Marchaim, Jason M. Pogue, George Alangaden, Hossein Salimnia, Dina Boikov, Shiri Navon-Venezia, Robert Akins, Philip Selman, Sorabh Dhar, Keith S. Kaye

^*Corresponding author for this work

Medicine, Hospital Medicine Division

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

A phenotypic and genotypic analysis of Acinetobacter baumannii was conducted from 2003 to 2008 in Detroit, MI. The incidence of A. baumannii increased from 1.7 to 3.7/1,000 patient days during the study period. Susceptibility to ampicillin-sulbactam and imipenem decreased from ∼90% to ∼40%. Genotyping revealed polyclonality, suggesting either emergence of multiple resistant strains or spread of a common genetic element. The sharp rise mandates major multidisciplinary interventions to optimize management of this multidrugresistant pathogen.

Original language	English (US)
Pages (from-to)	2235-2238
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	54
Issue number	5
DOIs	https://doi.org/10.1128/AAC.01665-09
State	Published - May 2010

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/AAC.01665-09

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Reddy, T., Chopra, T., Marchaim, D., Pogue, J. M., Alangaden, G., Salimnia, H., Boikov, D., Navon-Venezia, S., Akins, R., Selman, P., Dhar, S., & Kaye, K. S. (2010). Trends in antimicrobial resistance of Acinetobacter baumannii isolates from a Metropolitan Detroit health system. Antimicrobial agents and chemotherapy, 54(5), 2235-2238. https://doi.org/10.1128/AAC.01665-09

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abstract = "A phenotypic and genotypic analysis of Acinetobacter baumannii was conducted from 2003 to 2008 in Detroit, MI. The incidence of A. baumannii increased from 1.7 to 3.7/1,000 patient days during the study period. Susceptibility to ampicillin-sulbactam and imipenem decreased from ∼90% to ∼40%. Genotyping revealed polyclonality, suggesting either emergence of multiple resistant strains or spread of a common genetic element. The sharp rise mandates major multidisciplinary interventions to optimize management of this multidrugresistant pathogen.",

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AU - Salimnia, Hossein

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Trends in antimicrobial resistance of Acinetobacter baumannii isolates from a Metropolitan Detroit health system

Abstract

ASJC Scopus subject areas

UN SDGs

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