Trends of Gallbladder Cancer in Jordan Over 2 Decades: Where Are We?

Abdel Rahman Al Manasra*, Mohammed Bani Hani, Haitham Qandeel, Samer Al Asmar, Mohammad Alqudah, Nabil Al-Zoubi, Satish Nadig, Shadi Hamouri, Khaled Obeidat, Nada Al-Muqaimi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background and Study Aims: The prevalence of gallbladder cancer (GBC) varies between different parts of the world. This study is a review of literature and an update of a previously published study conducted in our university and aims to reassess the incidence of GBC over the past 2 decades. Patients and Methods: We conducted a retrospective study between 2002 and 2016. Data regarding demographics, clinical presentation, risk factors, histopathology, investigations, and treatments were obtained. A diagnosis of GBC established during surgery or primarily detected in the surgical specimen was classified as incidental. Results: Of 11 391 cholecystectomies performed, 31 cases (0.27%) of GBC were found. The mean age of patients with GBC was 68 years (43-103 years), 74% were women. The annual incidence of GBC was 0.2/100 000 (men: 0.1/100 000; women: 0.3/100 000). Biliary colic and acute cholecystitis were the main presentations. Diagnosis of GBC was “incidental” in 67% of cases. About 75% of patients with GBC had gallstones, 13% had polyps, and 3% had porcelain gallbladder. Adenocarcinoma was the dominant (87%) histologic type. Conclusions: The GBC rate in our region, similar to others parts of the world, is still low and has not changed over the past 2 decades. This study consolidates the previously published recommendations regarding the high index of suspicion of GBC in elderly with cholelithiasis.

Original languageEnglish (US)
JournalClinical Medicine Insights: Case Reports
Volume11
DOIs
StatePublished - Apr 19 2018
Externally publishedYes

Keywords

  • Gallbladder cancer
  • Jordan
  • jaundice

ASJC Scopus subject areas

  • General Medicine

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