Trizygotic quintuplet pregnancy following simultaneous embryo splitting in an oocyte donatin cycle

Paul A. Robb*, Daniel B. Williams, Jared C. Robins, Michael A. Thomas

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Purpose: To report a trizygotic quintuplet pregnancy following simultaneous embryo splitting in an oocyte donation cycle after transfer of 3 embryos. Methods: A 40-year-old Caucasian female G3P1 with two previous spontaneous abortions and diminished ovarian reserve presented for IVF. The patient underwent an oocyte donation cycle secondary to diminished ovarian reserve. Three embryos were transferred per patient request. Results: The three embryo transfer resulted in a trizygotic quintuplet pregnancy. Selective embryo reduction was performed at 11 weeks leaving a dizygotic twin gestation. The patient underwent SVD, or spontaneous vaginal delivery at 36 weeks gestation with respective weights and apgars of 2673 g (apgars 7(1), 9(5)) and 2722 g (apgars 7(1), 9(5)). The twins are presently doing well without complications. Conclusions: Although rare, the possibility of simultaneous embryo splitting must be factored into determining number of embryos for fresh transfer.

Original languageEnglish (US)
Pages (from-to)157-160
Number of pages4
JournalJournal of Assisted Reproduction and Genetics
Volume23
Issue number4
DOIs
StatePublished - Apr 1 2006

Keywords

  • Embryo splitting
  • Monozygotic
  • Multiple gestation
  • Quintuplet pregnancy

ASJC Scopus subject areas

  • Reproductive Medicine
  • Genetics
  • Obstetrics and Gynecology
  • Developmental Biology
  • Genetics(clinical)

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