Tubular biomarkers to assess progression of diabetic nephropathy

Gianfranco Tramonti, Yashpal S. Kanwar

Research output: Contribution to journalComment/debatepeer-review

17 Scopus citations

Abstract

Despite aggressive management, many patients with diabetic nephropathy still develop end-stage renal disease. Accompanying tubulointerstitial damage is important in the progression of diabetic nephropathy. Markers of tubular damage, such as NGAL, KIM-1, and LFABP, have been proposed for monitoring the effectiveness of therapy. However, Nielsen et al. report a lack of an independent correlation between these biomarkers and glomerular filtration rate. Therefore, these markers seem to offer no improvement in the management of diabetic nephropathy.

Original languageEnglish (US)
Pages (from-to)1042-1044
Number of pages3
JournalKidney international
Volume79
Issue number10
DOIs
StatePublished - May 2011

ASJC Scopus subject areas

  • Nephrology

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