Tumor acquisition for biomarker research in lung cancer

Marvaretta Stevenson*, Jared Christensen, Debra Shoemaker, Traci Foster, William T. Barry, Betty C. Tong, Momen Wahidi, Scott Shofer, Michael Datto, Geoffrey Ginsburg, Jeffrey Crawford, Thomas D'Amico, Neal Ready

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The biopsy collection data from two lung cancer trials that required fresh tumor samples be obtained for microarray analysis were reviewed. In the trial for advanced disease, microarray data were obtained on 50 patient samples, giving an overall success rate of 60.2%. The majority of the specimens were obtained through CT-guided lung biopsies (N = 30). In the trial for early-stage patients, 28 tissue specimens were collected from excess tumor after surgical resection with a success rate of 85.7%. This tissue procurement program documents the feasibility in obtaining fresh tumor specimens prospectively that could be used for molecular testing.

Original languageEnglish (US)
Pages (from-to)291-298
Number of pages8
JournalCancer Investigation
Issue number6
StatePublished - Jul 2014


  • Bioinformatics
  • Gene profiling
  • Lung cancer

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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