Tumor metastasis: A new twist on epithelial-mesenchymal transitions

Ann E. Vernon; Carole LaBonne

doi:10.1016/j.cub.2004.08.048

Tumor metastasis: A new twist on epithelial-mesenchymal transitions

Ann E. Vernon^*, Carole LaBonne

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Review article › peer-review

131 Scopus citations

Abstract

Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently been implicated in the onset of invasive behavior during tumor progression.

Original language	English (US)
Pages (from-to)	R719-R721
Journal	Current Biology
Volume	14
Issue number	17
DOIs	https://doi.org/10.1016/j.cub.2004.08.048
State	Published - Sep 7 2004

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)

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title = "Tumor metastasis: A new twist on epithelial-mesenchymal transitions",

abstract = "Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently been implicated in the onset of invasive behavior during tumor progression.",

author = "Vernon, {Ann E.} and Carole LaBonne",

year = "2004",

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T2 - A new twist on epithelial-mesenchymal transitions

AU - Vernon, Ann E.

AU - LaBonne, Carole

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N2 - Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently been implicated in the onset of invasive behavior during tumor progression.

AB - Epithelial-mesenchymal transitions are essential for normal embryonic development and for progression of non-invasive tumor cells into malignant, metastatic carcinomas. Twist, an important regulator of morphogenesis in the embryo, has recently been implicated in the onset of invasive behavior during tumor progression.

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JF - Current Biology

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Tumor metastasis: A new twist on epithelial-mesenchymal transitions

Abstract

ASJC Scopus subject areas

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