Tunable, Metal-Loaded Polydopamine Nanoparticles Analyzed by Magnetometry

Zhao Wang, Yijun Xie, Yiwen Li, Yuran Huang, Lucas R. Parent, Treffly Ditri, Nanzhi Zang, Jeffrey D. Rinehart*, Nathan C. Gianneschi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

57 Scopus citations


We report the preparation and study of Mn(III)-, Fe(III)-, Co(II)-, Ni(II)-, Cu(II)-, Zn(II)-, and Ga(III)-loaded polydopamine nanoparticles (PDA-NPs) via autoxidation polymerization of metal-dopamine complexes in the presence of free dopamine. An analysis of the doping range and parameters that influence final particle morphology is presented. In addition, magnetometry provides a probe of the general electronic structure and electronic interactions for Mn(III)-, Ni(II)-, and Co(II)-loaded PDA-NPs. PDA-NPs doped with Mn(III) are found to have high spin, low anisotropy, and weak magnetic coupling and are therefore predicted to have superior relaxivity behavior compared to previously studied Fe(III)-loaded PDA-NPs. Comparison of Mn(III)- and Fe(III)-loaded PDA-NP relaxivity confirms the predictive ability of the magnetometry measurements.

Original languageEnglish (US)
Pages (from-to)8195-8201
Number of pages7
JournalChemistry of Materials
Issue number19
StatePublished - Oct 10 2017

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)
  • Materials Chemistry


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