Turning down the volume on transcriptional noise

Daniel Neems*, Steven T Kosak

*Corresponding author for this work

Research output: Contribution to journalShort survey

4 Scopus citations

Abstract

Transcriptional noise has an important role in generating diversity in cellular populations that are seemingly identical. As this noise stems from the inherent stochasticity of gene expression, it has been unclear whether it is directly controlled. Dig1, a regulator of the budding yeast mating pathway, is now shown to prevent transcriptional noise by regulating the spatial organization of downstream gene targets.

Original languageEnglish (US)
Pages (from-to)929-931
Number of pages3
JournalNature Cell Biology
Volume12
Issue number10
DOIs
StatePublished - Oct 1 2010

ASJC Scopus subject areas

  • Cell Biology

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