Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Fixed-focus and antenna-array sensors

Susan C. Hagness; Alien Taflove; Jack E. Bridges

doi:10.1109/10.730440

Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Fixed-focus and antenna-array sensors

Susan C. Hagness^*, Alien Taflove, Jack E. Bridges

^*Corresponding author for this work

Electrical and Computer Engineering

Research output: Contribution to journal › Article › peer-review

484 Scopus citations

Abstract

A novel focused active microwave system is investigated for detecting tumors in the breast. In contrast to X-ray and ultrasound modalities, the method reviewed here exploits the breast-tissue physical properties unique to the microwave spectrum, namely, the translucent nature of normal breast tissues and the high dielectric contrast between malignant tumors and surrounding lesion-free normal breast tissues. The system uses a pulsed confocal technique and time-gating to enhance the detection of tumors while suppressing the effects of tissue heterogeneity and absorption. Using published data for the dielectric properties of normal breast tissues and malignant tumors, we have conducted a two-dimensional (2-D) finite-difference timedomain (FDTD) computational electromagnetics analysis of the system. The FDTD simulations showed that tumors as small as 2 mm in diameter could be robustly detected in the presence of the background clutter generated by the heterogeneity of the surrounding normal tissue. Lateral spatial resolution of the tumor location was found to be about 0.5 cm.

Original language	English (US)
Pages (from-to)	1470-1479
Number of pages	10
Journal	IEEE Transactions on Biomedical Engineering
Volume	45
Issue number	12
DOIs	https://doi.org/10.1109/10.730440
State	Published - 1998

Funding

Manuscript received November 4, 1997; revised May 27, 1998. This work was supported by the National Institutes of Health (NIH) under Phase-I SBIR Grant 1R43CA67598 01A2. Asterisk indicates corresponding author. *S. C. Hagness is with the Department of Electrical and Computer Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706 USA (e-mail: [email protected]). A. Taflove is with the Department of Electrical and Computer Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208 USA. J. E. Bridges is with Interstitial, Inc., Park Ridge, IL 60068 USA. Publisher Item Identifier S 0018-9294(98)08848-X.

Keywords

Biomédical electromagnetic imaging
Cancer
FDTD methods
Microwave antenna arrays
Numerical analysis
Scattering
Tumors

ASJC Scopus subject areas

Biomedical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/10.730440

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title = "Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Fixed-focus and antenna-array sensors",

abstract = "A novel focused active microwave system is investigated for detecting tumors in the breast. In contrast to X-ray and ultrasound modalities, the method reviewed here exploits the breast-tissue physical properties unique to the microwave spectrum, namely, the translucent nature of normal breast tissues and the high dielectric contrast between malignant tumors and surrounding lesion-free normal breast tissues. The system uses a pulsed confocal technique and time-gating to enhance the detection of tumors while suppressing the effects of tissue heterogeneity and absorption. Using published data for the dielectric properties of normal breast tissues and malignant tumors, we have conducted a two-dimensional (2-D) finite-difference timedomain (FDTD) computational electromagnetics analysis of the system. The FDTD simulations showed that tumors as small as 2 mm in diameter could be robustly detected in the presence of the background clutter generated by the heterogeneity of the surrounding normal tissue. Lateral spatial resolution of the tumor location was found to be about 0.5 cm.",

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note = "Funding Information: Manuscript received November 4, 1997; revised May 27, 1998. This work was supported by the National Institutes of Health (NIH) under Phase-I SBIR Grant 1R43CA67598 01A2. Asterisk indicates corresponding author. *S. C. Hagness is with the Department of Electrical and Computer Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706 USA (e-mail: [email protected]). A. Taflove is with the Department of Electrical and Computer Engineering, McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL 60208 USA. J. E. Bridges is with Interstitial, Inc., Park Ridge, IL 60068 USA. Publisher Item Identifier S 0018-9294(98)08848-X.",

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PY - 1998

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N2 - A novel focused active microwave system is investigated for detecting tumors in the breast. In contrast to X-ray and ultrasound modalities, the method reviewed here exploits the breast-tissue physical properties unique to the microwave spectrum, namely, the translucent nature of normal breast tissues and the high dielectric contrast between malignant tumors and surrounding lesion-free normal breast tissues. The system uses a pulsed confocal technique and time-gating to enhance the detection of tumors while suppressing the effects of tissue heterogeneity and absorption. Using published data for the dielectric properties of normal breast tissues and malignant tumors, we have conducted a two-dimensional (2-D) finite-difference timedomain (FDTD) computational electromagnetics analysis of the system. The FDTD simulations showed that tumors as small as 2 mm in diameter could be robustly detected in the presence of the background clutter generated by the heterogeneity of the surrounding normal tissue. Lateral spatial resolution of the tumor location was found to be about 0.5 cm.

AB - A novel focused active microwave system is investigated for detecting tumors in the breast. In contrast to X-ray and ultrasound modalities, the method reviewed here exploits the breast-tissue physical properties unique to the microwave spectrum, namely, the translucent nature of normal breast tissues and the high dielectric contrast between malignant tumors and surrounding lesion-free normal breast tissues. The system uses a pulsed confocal technique and time-gating to enhance the detection of tumors while suppressing the effects of tissue heterogeneity and absorption. Using published data for the dielectric properties of normal breast tissues and malignant tumors, we have conducted a two-dimensional (2-D) finite-difference timedomain (FDTD) computational electromagnetics analysis of the system. The FDTD simulations showed that tumors as small as 2 mm in diameter could be robustly detected in the presence of the background clutter generated by the heterogeneity of the surrounding normal tissue. Lateral spatial resolution of the tumor location was found to be about 0.5 cm.

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KW - Scattering

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Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: Fixed-focus and antenna-array sensors

Abstract

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Keywords

ASJC Scopus subject areas

UN SDGs

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