Type 2 diabetes and colorectal cancer screening: Findings from the English Longitudinal Study of Ageing

Christian von Wagner*, Dorina Cadar, Ruth A. Hackett, Panayotes Demakakos, Rebecca J. Beeken, Stacy Cooper Bailey, Michael Wolf, Andrew Steptoe, Cristina Renzi, Sandro T. Stoffel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: Type 2 diabetes has been identified as a risk factor for colorectal cancer, but little is known about whether it influences participation in colorectal cancer screening programmes. This study tested the extent to which Type 2 diabetes is negatively associated with colorectal cancer screening uptake. Methods: We analysed individual data of screening eligible men and women aged 60–75 without cancer diagnosis from wave 6 of the English Longitudinal Study of Ageing (collected 2012–2013), to investigate whether Type 2 Diabetes influences colorectal cancer screening behaviour independently of demographic characteristics, body mass index, socio-economic status and other chronic diseases. Results: Individuals who reported to have Type 2 diabetes or had glycated haemoglobin (HbA1c) levels of 48 mmol/mol or higher were less likely to have ever completed a screening test (faecal occult blood test; 62.8% vs. 75.8%, p < 0.01) or to be up-to-date with their biennial screening invitation (60.2% vs. 72.0%, p < 0.05). The negative associations of Type 2 diabetes on colorectal cancer screening were found both in unadjusted and adjusted regression models. Conclusions: Future qualitative and quantitative research should identify reasons for this discrepancy, to inform interventions to increase screening uptake in this high-risk population.

Original languageEnglish (US)
JournalJournal of Medical Screening
DOIs
StateAccepted/In press - 2019

Keywords

  • Bowel cancer
  • bowel cancer screening
  • colorectal cancer screening
  • comorbidities
  • diabetes
  • screening participation

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Type 2 diabetes and colorectal cancer screening: Findings from the English Longitudinal Study of Ageing'. Together they form a unique fingerprint.

Cite this